virtual seminars it couldn't be easier

In Vitro Toxicity Assay Design and Hit Profiling

Design of effective toxicology programs for large-scale screening and compound development

Speaker:
Jeffrey R. Haskins, Ph.D.
Vice President
Technology and Product Development
Cellomics

Moderator:
David Monteith, Ph.D., DABT
Principal Research Scientist, Toxicology and Drug Disposition
Eli Lilly & Co.

Registration for the live event is now closed. However, if you are interested in viewing an online recording which contains the entire presentation, including audio, you may purchase this for $169 USD. Please click the button below and you will be emailed information on how to access the recorded event. MAC USERS: Unfortunately at this time the recordings cannot be viewed on the MAC OS.

Well-designed in vitro toxicity assays can be the main deciding factors in the ultimate fate of pipeline compounds. This virtual seminar will provide instructional guidance on the design of toxicology assays that best capitalize on in vitro biodata.

Data derived from critical, early physiological indicators and from postmortem indicators are crucial components of effective assay design. Fruitful application of this information relies on selection of the appropriate parameters for development of live-cell detection techniques that in turn delineate the sequence of events leading to terminal toxicity.

Sequence and biology information can then be converted into fixed–end-point assays applicable to large-scale screening efforts. Kinetic profiling of hits provides yet further relevant information for subsequent compound development. These topics, and a discussion of novel methods including micronucleus assays, will be presented.

The 1½–hour presentation will address:

  • Key physiological and postmortem cytotoxicity indicators for toxicity assay design
  • Live-cell detection techniques to elucidate cell-death events
  • Design of fixed–end-point assays for large-scale screening
  • Kinetic profiling of toxicity-assay hits
  • Automated assay platforms for monitoring micronucleus formation (a hallmark of genetic toxicity)

Ample time is allotted for an extensive Q&A session, with worldwide participation.

Participate in this Virtual Seminar on In Vitro Toxicity Assay Design and Hit Profiling. You can attend this tutorial from anywhere you have an Internet connection.

One Low Registration Fee of $149 entitled you to a site registration, which enables you and unlimited additional colleagues and staff to participate, whether gathered around a computer or in a conference room with speakerphone and screen.

It Couldn’t Be Easier! You’ll view the presentation over your Web browser. On a separate telephone line (which can be put on speakerphone), you will hear the audio and be able to ask questions of the presenter and moderator. You can also submit questions by your keyboard.

Time Well Spent! No travel, no time away. GEN’s hour-and-a-half virtual seminars are authoritative presentations by industry leaders that include ample time for questions and discussion. Registrations will be limited to ensure interactive participation.

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